FOXO Club
FOXO Club AI Research

Decoding the Biology
of Longevity
with Artificial Intelligence

We apply cutting-edge AI to understand the mechanisms of ageing — identifying biomarkers, predicting healthspan trajectories, and accelerating the science of living better, longer.

Rooted in longevity science. Powered by machine learning.Guided by the FOXO proteins that regulate life itself.

4AI Focus Areas
2025Founded
Potential
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AI Research Areas

Where We Focus
Our Intelligence

Six interconnected research programmes — each targeting a different layer of the longevity problem, all powered by AI.

Foundation Research

Longevity AI

We train large-scale models on multi-omic datasets to identify the molecular hallmarks of ageing — mapping how FOXO pathways shift across the lifespan and which interventions restore youthful gene expression.

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Data Science

Biomarker Analysis

Our AI systems analyse thousands of biomarkers simultaneously — blood panels, proteomics, metabolomics — clustering biological age signatures and surfacing early indicators invisible to standard clinical assays.

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Machine Learning

Predictive Health

Using deep learning on longitudinal health data, we build individual trajectory models that predict healthspan divergence years before symptoms emerge — enabling precision longevity strategies.

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Computational Biology

Drug Discovery

We apply AI to compress the longevity drug discovery cycle — screening compound libraries for FOXO-pathway activity, predicting off-target effects, and prioritising candidates for experimental validation.

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Bioinformatics

Epigenetic Clocks

We build and validate next-generation epigenetic clocks trained on methylation arrays across diverse populations — producing biological age scores that outperform chronological age in predicting disease onset and mortality.

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Applied AI

Clinical Trials AI

Our AI platform accelerates longevity trial design — optimising cohort selection, adaptive dosing protocols, and real-time safety monitoring so promising interventions reach validation faster with smaller, more informative studies.

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